Adult
Nitazoxanide
Warning
General Information
Nitazoxanide supply varies worldwide. Consult pharmacy before starting treatment.
Restricted formulary antimicrobial: For details see OUH netFormulary
For all information regarding contra-indications, interactions, contraception, pregnancy and breastfeeding and additional information, see BNF and Summary of Product Characteristics (SPC).
Standard dose
Nitroimidazole resistant giardiasis: 500mg po bd for 3 days with food
Eradication of intraluminal Entamoeba histolytica cysts: 500mg po bd for 3 days with food
Refractory diarrhoea caused by Cryptosporidium species in immunocompetent adults: 500mg po bd po for 3 days with food
Renal and hepatic impairment
Renal impairment
No dose adjustment necessary
Hepatic impairment
No dose adjustment necessary
- Sanford guide says use with caution but not stated in other resources.
References
- Freedman D. Sanford Guide – Nitazoxanide. Last revision of the text 2/12/24. Accessed on-line on 24th February 2025.
- FDA. Nitazoxanide data sheet. Last revised 12/2021. Accessed 24/2/25 at https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/021497s017lbl.pdf
- Uptodate. Nitazoxanide. Version 237. Accessed on-line on 24/2/25.