Adult

Rezafungin

Warning

General Information

Echinocandin

Restricted formulary antimicrobial: For details see OUH netFormulary 

For all information regarding contra-indications, interactions, contraception, pregnancy and breastfeeding and additional information, see BNF and Summary of Product Characteristics (SPC).

Standard dose

Day 1 of treatment

(Loading)

400mg iv single dose  

Day 8 of treatment and onwards

(Maintenance)

200mg iv on day 8 and then once weekly

 

 

Obesity

No dose adjustment required

Renal and hepatic impairment

Renal impairment

No dose adjustment required

 

Hepatic impairment

No dose adjustment required

Additional information

The OUH Antifungal Patient Information Leaflet can be found HERE

References

  • Napp Pharmaceuticals Limited. Summary of Product Characteristics. Rezzayo 200 mg powder for concentrate for solution for infusion [online]. Last revision of the text: 29/1/24. Accessed via: https://www.medicines.org.uk/emc#gref Accessed:17/3/25.
  • BNF online accessed via www.medicinescomplete.com. Accessed:11/02/25
  • Sanford Guide. Rezafungin [Internet] Last revision of the text: 5/2/25
  • Sanford Guide. Obesity dosing adjustment [Internet] Last revision of the text: 23/2/25 
  • Drugs and Lactation Database (LactMed). Rezafungin [Internet] Last updated May 2023

Editorial Information

Next review date: 06 Mar 2028