Adult
Terbinafine
Warning
General Information
Allylamine antifungal
Restricted formulary antimicrobial: For details see OUH netFormulary
For all information regarding interactions, contraception, pregnancy and breastfeeding and additional information, see BNF and Summary of Product Characteristics (SPC).
Standard dose
|
|
Oral dose |
|
Standard dose |
250mg OD |
Renal and hepatic impairment
Renal impairment
|
Creatinine Clearance (mL/min)* |
Dose |
|
More than 50 |
Dose as in normal renal function |
|
20-50 |
Give the full dose on alternate days |
|
Less than 20 |
Give the full dose on alternate days |
|
HD/HDF/High Flux/PD |
Dose as in creatinine clearance less than 20 mL/min |
*Dose ranges use creatinine clearance, rather than eGFR
Note: Doses are based on Renal Drug Database
Hepatic impairment
Avoid use in chronic or active liver disease.
References
- Aurobindo Pharma – Milpharm Ltd. Terbinafine 250mg Tablet summary of product characteristics. Electronic Medicines Compendium. 2025. Last revision of the text 4/6/25. Accessed via https://www.medicines.org.uk Accessed 3/4/26.
- British National Formulary. Terbinafine. BNF online accessed via www.medicinescomplete.com Accessed 3/4/26
- The Renal Drug Database. Terbinafine. Last updated 14/11/24. Accessed via https://renaldrugdatabase.com Accessed 3/4/26
- Sanford guide [online]. Terbinafine. Last updated 31/3/26. Accessed via https://webedition.sanfordguide.com Accessed 3/4/26