Adult

Tobramycin

General Information

Aminoglycoside

Restricted formulary antimicrobial: For details see OUH netFormulary

AWaRe antibiotic classification: 'Watch'. Use as per guidelines or Micro/ID advice.

For all information regarding contra-indications, interactions, contraception, pregnancy and breastfeeding and additional information, see BNF and Summary of Product Characteristics (SPC).

Standard Dose

Discuss dose with Micro/ID

Renal and hepatic impairment

Discuss with pharmacy or Micro/ID

MHRA Drug Safety Updates

MHRA Drug Safety Update (January 2021) Aminoglycosides (gentamicin, amikacin, tobramycin, and neomycin): increased risk of deafness in patients with mitochondrial mutations

References

  1. MHRA. Drug Safety update (January 2021) Aminoglycosides (gentamicin, amikacin, tobramycin, and neomycin): increased risk of deafness in patients with mitochondrial mutations. Accessed at https://www.gov.uk/drug-safety-update/aminoglycosides-gentamicin-amikacin-tobramycin-and-neomycin-increased-risk-of-deafness-in-patients-with-mitochondrial-mutations Accessed 29/9/26

Editorial Information

Last reviewed: 29 Sept 2026

Next review date: 19 Sept 2029

Author(s): AMST.